AAV VECTORS PSEUDOTYPED WITH CAPSIDS FROM PORCINE AND BOVINE SPECIES MEDIATE IN VITRO AND IN VIVO GENE DELIVERY

AAV Vectors Pseudotyped with Capsids from Porcine and Bovine Species Mediate In Vitro and In Vivo Gene Delivery

Adeno-associated virus (AAV) vectors are among the most widely used delivery vehicles for in vivo gene therapy as they mediate robust and sustained transgene expression with limited toxicity.However, a significant impediment to the broad clinical success of AAV-based therapies is the widespread presence of pre-existing humoral immunity to AAVs in t

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Structure and distribution of function between the stages of the information and measurement system for diagnostics of traction substations and contact network installations

The article presents the results of the study of the multistage information-measuring system (IMS) of the diagnostic of traction power supply objects combined with the operational-dispatch control allowing to ensure reliability, attributing to unit value of the IMS.Taking into account the introduction of functional redundancy in the structure of du

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